Tuesday, October 24, 2006

hiv structure and life cycle

LinkHIV is an enveloped RNA virus:
As HIV buds out of the host cell during replication,
it acquires a phospholipid envelope.
Protruding from the envelope are peg-like structures
that the viral RNA encodes.
Each peg consists of three or four gp41 glycoproteins (the stem),
capped with three or four gp120 glycoproteins.
Inside the envelope the bullet-shaped nucleocapsid of the virus
is composed of protein, and surrounds two single strands of RNA.
Three enzymes important to the virus's life cycle -
reverse transcriptase
, integrase, and protease -
are also within the nucleocapsid.


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